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by Marijana Domazet, Tuesday, 30 July 2013 | Categories: Cialis

In the past, there have been several reports about the variation in outcome from taking PDE5 inhibitors, such as tadalafil that is the active ingredient in Cialis, on an as-needed basis. While some men have been able to return to normal erectile functioning, others have reported less than optimal results. However, recently a study came out to suggest that regularly taking PDE5 inhibitors significantly improved a patient’s outcome.

The study, which was published in Journal of Sexual Medicine, was a randomized, double blind trial that was carried out in a total of 51 sites in the US and Canada. Overall, 623 men over the age 18 with ILEF-EF scores between 17 and 26 took part. ILEF-EF is a questionnaire that is commonly used in research to establish sexual function. Higher results on it indicate better sexual function. The men were randomly assigned to one of two groups which either received tadalafil or a placebo treatment that was to be used daily. The men in the tadalafil group were further split into groups that received 2.5 mg dosages and 5 mg dosages. The researchers measured their ILEF-EF scores before the start of the study and after the treatment. The key findings indicated that a significant number of men in both treatment groups were able to return to ILEF-EF scores in the normal range after 12 weeks. Specifically, this was the case for 38.7% of the men in the 2.5 mg group and 39.6% in the 5mg group. In contrast to that, only 12.1% participants in the placebo group received similar results. Lastly, it is worth mentioning that all the mentioned findings were statistically significant. Based on this the researchers concluded that the use of tadalafil could be beneficial for men whose ILEF-EF scores were below the threshold for erectile dysfunction.

These findings are encouraging, as the study utilised a double blind placebo-treatment design. Although it is fair to say that more studies are needed to replicate the current findings, the use of ILEF has placed the current study in good stand to be compared to previous research. It is our hope that the current findings are given their due weight in clinical assessments when the issue of dosages and prescription arises. Further details of the study can be read here.




by Robert MacKay, Monday, 24 September 2012 | Categories: Cialis

The Committee for medicinal products for Human Use (CHMP) has recommended the approval of the erectile dysfunction treatment, Cialis 5mg once a day, for the treating of benign prostatic hyperplasia (BPH). The Food and Drug Administration (FDA) in the States has already approved the drug for treating those who experience the symptoms of this condition.

Those who take nitrates, which are typically used in the treating of chest pain and also used in poppers, will be contraindicated for Cialis as the combination of the drug and nitrates are said to cause the level of blood pressure to drop dramatically.

The CHMP announced its recommendation after data concerning safety and efficacy from 1,500 patients, over 4 clinical studies, had been reviewed.




by Robert MacKay, Sunday, 16 October 2011 | Categories: Cialis

The Food and Drug Administration have announced that it has given Eli Lily’s successful erectile dysfunction drug, Cialis, the go ahead for the treating of enlarged prostate, benign prostatic hyperplasia, BPH, and with men who suffer from erectile dysfunction, they will experience double the benefit from this treatment.

Phase III trials revealed that the 5mg, once daily consumption of tadalafil (Cialis’ active ingredient) improved symptoms associated with both conditions significantly.

BPH causes men to experience sudden urges to pass urine and more frequently during the night. There are a few treatments on the market for BPH however none have been approved to treat both conditions simultaneously.

Cialis was already hot on the heels of Viagra and set to become the most popular of the erectile dysfunction treatments and now with the FDA’s approval for its alternative use, the bar has been raised even higher.




by Robert MacKay, Thursday, 14 July 2011 | Categories: Cialis

Cialis has overtaken Viagra and is on its way to becoming the new name on everyone’s lips having more prescriptions filled than Viagra this year internationally. 5 years after Viagra was launched, Cialis was born and Lily, the eager pharmaceutical company pulled out all the stops at that time in order to help Cialis edge its way in to an already buzzing market. This year sales have increased by 9% on the year before and numbers continue to rise.

Their biggest selling point is the much longer period of duration of Cialis. This means that the effects of Cialis will last 36 hours compared with Viagra’s 4 hour window. Furthermore, Tadalafil (the active ingredient) has other uses and Lily is pushing for it to be sold as a treatment for hypertension in Europe. In the US it is hoping for approval as a drug for prostate enlargement which is often associated with erectile dysfunction.

The question is will the emergence of generic Viagra next year prompt a decline in Cialis sales. For now, ‘Le weekend pill’ is still going strong.




by Robert MacKay, Tuesday, 29 June 2010 | Categories: Cialis | General Health

We have seen an alert from Australia about a product called Cialis 50. The product is sold as an aid for erectile dysfunction but is totally unrelated to the prescription medication called Cialis. Cialis 50 came to prominence a few days ago when an Australian truck driver was admitted to a hospital in Queensland with slurred speech and profuse sweating. It then transpired that the 54 year old truck driver had taken the fake erectile dysfunction medication that had been sold illegally.

This case highlights the dangers of buying counterfeit medication. Many people are tempted to go down the counterfeit route because the fakes are a fraction of the price of the real thing. As you can see from this story, saving a few pounds may do nothing for your health. The Online Clinic is happy to support the Get Real campaign, which aims to educate people on how to get a legitimate prescription, either online or in person. The UK healthcare industry is highly regulated so it could not be easier trying to sort the “Viagra Cowboys” out from the legitimate healthcare providers such as The Online Clinic. Make sure that the clinic that you are dealing with is registered with the Care Quality Commission. We carry their logo on our home page and publish our certificate number so that you can check us out with the regulator. Avoid anyone who does not have a certificate as they are operating illegally.




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