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As a regulated clinic we are able to prescribe slimming pills to help you lose weight. We offer a free, no obligation online consultation to check your suitability. Next day delivery in the UK is guaranteed.

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Our Diet and Slimming Pill Policy

We believe that the best way to lose weight is by following a healthy eating plan and taking a moderate amount of exercise every day, as laid out on the obesity advice page on our website. Where an effort in this direction has failed to produce significant results or you just need that extra push, we will be happy to help you achieve your goals with slimming pills so long as we agree that it is an appropriate course of action based on your personal circumstances. However, as a regulated clinic, we will only ever advise you on prescription medications that have been through exhaustive clinical trials to demonstrate their safety and efficacy. We never recommend herbal diet or slimming pills or anything that you can buy over the counter because they tend to be ineffective or non-proven because of the lack of clinical data.

Prescription Slimming Pills

There are only two prescription slimming pills currently licensed in the UK for medium term use with a demonstrated safety and efficacy levels. There are a number of new slimming pills that may come under consideration by the regulatory authorities in the EU soon and we can notify you when (and if) they become available to prescribe if you take a few moments to register with us.

The medications licensed and available to prescribe are: Xenical (orlistat) and Mysimba. The weight loss injection, Saxenda is also available through The Online Clinic.


Xenical (also known as Orlistat) is a slimming medication, which works in a localised way to prevent the digestion and absorption of a degree of dietary fat. As the medication works locally in the digestive tract, there tend to be fewer potential side effects associated with this medication than with its centrally acting competitor. All medications have potential side effects but for most patients the side effects experienced with Xenical will normally disappear with an adjustment to diet.

Because of the way that Xenical works, it is essential that you make sure that you have a mildly low fat diet before you begin taking the medication. Many people mistakenly think that Xenical is only suitable for people with a high fat diet – nothing could be further from the truth! If you have a high fat diet and you take Xenical, you are most likely to experience undesirable gastrointestinal side effects such as very loose bowel movements and an urgency to have them. So long as you follow the dietary advice, you should avoid these side effects.

Xenical may not be suitable for everyone and it is only available on prescription. Some pharmacies have a special dispensation to provide Xenical under Patient Group Direction so it is available in certain places in the UK following an interview with a pharmacist. We provide the medication on prescription following an online consultation with a registered doctor.

Orlistat is available as Alli, an over the counter pharmacy slimming pill, which contains 60 mg of Orlistat rather than 120 mg when it is prescribed as Xenical. Given the dosage difference, Xenical is a more effective slimming tablet than Alli.

We have provided further information on Xenical, which is based on the approved patient information leaflet, which accompanies the medication.


Mysimba was launched in the UK in 2017. This medication is an appetite suppressant so it is more effective for people who have a problem controlling the amount that they eat.

Mysimba requires a gradual increase in the dosage, so patients are asked to titrate over a period of 4 weeks to get to the normal maintenance dose. A failure to follow these instructions could lead to unwanted side effects. The most common side effect is nausea but this can generally be managed by taking the medication with food and/or extending the titration period.

Mysimba is currently the only oral appetite suppressant licensed in the UK. You can find out more about this medication here.


Saxenda is an appetite suppressant that is administered by way of a daily injection. This is not as scary as it sounds! The medication is contained in a pre-loaded injection pen and the needles are very fine and are not painful to administer. Patients are instructed to inject just under the skin of the abdomen, changing injection sites each time.

Saxenda is one of the most popular medications that we can prescribe for weight loss as it is very effective and is usually well tolerated.

Like Mysimba, patients need to increase the dosage gradually and there is dial on the injection pen to make this really easy. It takes 4 weeks to reach the maintenance dose.

More information on Saxenda.

The two medications that are likely to come under consideration of the European Medicines Agency are:


This is a centrally acting drug that is a completely new compound. Weight loss was moderate in clinical trials but above the minimum level required of a weight loss medication before approval is given. The FDA had raised concerns about mammary tumours in rats during Phase I studies. These were thought to be caused by extended exposure to high levels of prolactin. The mechanism that causes these tumours may not be relevant to humans as there are a number of currently licensed drugs that had this effect on rodents but not on humans. The FDA eventually granted a licence for the product but there is no equivalent licence in Europe at this time.

Click here for further information on Lorcaserin.


Qsiva is a new medication that combines a low dose of Phentermine with Topiramate. Qsiva acts as an appetite suppressant and had very high levels of sustained weight loss in clinical trials. The FDA was concerned about the possibility of birth defects so they asked for further information. Concern was also raised earlier about cardiovascular risk but there were no particular issues identified during the two year phase III clinical trial. The application to the FDA was granted but the one to the European Medicines Agency was rejected. We believe a new application will be submitted shortly.

Please follow this link to get further information on Qsiva.

If you would like a consultation to help you lose weight then please click on the Free Consultation button below. If you ask to be put on our mailing list during the registration process then we can let you know when (and if) the above new medications become available to prescribe.

Free Online Assessment Quick and Without Obligation

Slimming Pills News

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  • Contrave to Apply for European License

    It is a while since we last reported on Contrave, the experimental weight loss medication concocted by Orexigen Therapeutics from two existing medications: bupropion and naltrexone.  The medication met the FDA's minimum efficacy requirements for a weight loss medication, even although the…

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