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Miconazole Oral Gel

Miconazole oral gel is an antifungal medicine, which is active against infections caused by the presence of fungi, yeasts and some bacteria.

Can I buy Miconazole oral gel online?

The doctors at The Online Clinic can prescribe this medication for oral thrush. Please complete an online consultation form to commence the process.

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What is Miconazole oral gel?

Miconazole is the active component in this oral gel preparation. You may also see Miconazole referred to as Daktarin.

Miconazole oral gel is used for the treatment of fungal and yeast infections of the mouth through to and including your gut. Miconazole prevents fungi from making a product called ergosterol, which is a fat needed for healthy fungal cell membranes (cholesterol has a similar function in animal cell membranes). The faulty cell membranes develop holes, so the contents of the cells leak out, and ultimately result in the cells’ death. By killing fungal and yeast cells, the infection clears up.

Additionally, Miconazole acts as an antibacterial agent, targeting some bacteria (gram-positive bacteria) that may occur in the infection.

How to use Miconazole oral gel

Miconazole oral gel is taken by mouth, where it is kept for as long as you can before swallowing. Wash your hands and pierce the top of the tube using the cap. If you have a mouth infection only, apply the gel to the area of infection using your finger. If you have dentures, take them out at night and rub the gel on them to prevent the spread of infection. When giving the gel to children, put the gel just inside the mouth. Miconazole oral gel is gluey so ensure the child does not choke.

Each person will have their own Miconazole oral gel treatment schedule given to them by their doctor. This medicine is used after meals. It is used for 7 days or more after the infection has cleared to ensure that it does not return.

  • With mouth and throat infections, adults and children aged 2 years or older usually use 2.5 ml of gel four times daily; children aged 4 months to 2 years use 1.25 ml of gel four times daily.
  • With stomach and gut infections, adults and children older than 4 months usually use 20 mg of gel per kg of body weight each day, which is divided into four equal doses per day (to a maximum of 10 ml taken four times daily).
  • Premature or late developing infants aged 4 to 6 months must be reviewed by a doctor before taking Miconazole oral gel.

In cases where a dose of Miconazole oral gel is missed, forget that dose; use the gel at the prescribed dose (not twice as much) at the next scheduled time. Seek medical attention immediately if you take more gel than prescribed.

Who can use Miconazole oral gel?

Adults and children older than 4 months old may use Miconazole oral gel.

This oral gel cannot be used by people with an allergy to Miconazole, a similar antifungal treatment or to any one of the gel’s other constituents. Inform your doctor if you have problems with your liver before taking the medicine.

All your current, recent and known future medicines must be discussed with your doctor, as many have potential to change Miconazole’s action. Miconazole oral gel cannot be used if you also take the following specific treatments: lovastatin/simvastatin (for lower cholesterol); quinidine/dofetilide (for arrhythmias); cisapride (for digestion); midazolam/triazolam (for anxiety, sleeplessness); pimozide/sertindole (for mind and behavioural disturbances); ergotamine (for migraine); and astemizole/mizolastine/terfenadine (for allergies).

You must also inform your doctor or dentist that you are taking any of the following medicines: other anti-infectives (specifically: protease inhibitors [e.g., saquinivir] for HIV infection; rifabutin for tuberculosis; and trimetrexate for pneumonia); blood thinners (anticoagulants, e.g., warfarin); heart and blood vessel medicines (calcium channel blockers, e.g. verapamil, dihydropyridines); cancer therapies (e.g., vinca alkaloids, busulfan, docetaxel); antidepressants, anxiolytics, or tranquillisers (e.g., reboxetine, alprazolam, brotizolam, buspirone); post-organ transplant therapies (cyclosporin, rapamycin, tacrolimus); anti-epileptics (carbamazepine, phenytoin); pain (alfentanil) and inflammation (methylprednisolone); antidiabetic agents (sulphonylureas, e.g., chlorpropamide, glibenclamide); anti-allergy medicine (ebastine); and medicines for erectile dysfunction (sildenafil).

Pregnancy (in both the planning or during stages) and breastfeeding must always be discussed with your doctor before taking Miconazole oral gel. Do not treat a breastfeeding child prescribed Miconazole oral gel with this medicine by applying it to your nipple.

Miconazole oral gel side effects

Stop treatment and get immediate medical assistance if you experience signs of an allergic reaction, such as a swollen face, lips, or tongue, or swelling of the throat; itchy raised lumps (similar to a nettle rash); breathing problems; or your skin becomes very itchy, red and blistered. Also stop this treatment if :

  1. Your skin starts to peel or gets pus-filled pimples;
  2. You acquire Stevens-Johnson Syndrome that comprises blisters on skin, eyes, mouth, and genital areas;
  3. You feel light headedness, and generalised itchiness and breathing problems; and
  4. You are taking blood thinners and get unexpected bleeding problems, e.g., bruising, nosebleeds, or blood in spit, vomit, urine, or stools (blood is black in colour).

Common side effects include discomfort in the mouth, regurgitation, nausea, and vomiting, and the gel tastes peculiar. Some people state that they lose their normal sense of taste. A few individuals experience sore mouth, tongue discolouration, choking, diarrhoea, hepatitis (inflamed liver), pus-filled pimples or blisters.

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Reviewed by: Dr Loraine Haslam MBBS, DRCOG, DFSRH, LoC SDI, LoC IUT, MRCGP
GMC registration number: 4524038
Date: 21 September 2022
Next review: 20 September 2024
All UK registered doctors can have their registration checked on
The Medical Register at the GMC website.

Information Leaflet

Source and further information

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