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posted: Thursday, February 18, 2010 | Categories: Erectile Dysfunction | Priligy

With Johnson and Johnson still waiting for approval from the FDA for their premature ejaculation pill Priligy in the U.S, they are not going to be best pleased by the news that an Atlanta firm is also planning on seeking approval for an aerosol designed to combat the same condition.

Sciele Pharma has developed a metered-dose aerosol spray which when sprayed onto the skin is meant to increase latency time.  If approved, it will go head-to-head with Priligy to conquer the P.E market, which could be extremely lucrative.

A representative from the company, Joseph T Schepers, told the New York Times that premature ejaculation was in fact more common that erectile dysfunction (characterised by an inability to achieve an erection sufficient for penetration, rather than an inability to control ejaculation)  with 1 in 3 men suffering from it.

While there has been a certain amount of debate about whether premature ejaculation merits medical intervention, the International Society for Sexual Medicine defines it as ‘characterised by ejaculation which always or nearly always occurs prior to or within one minute of vaginal penetration’. They added that sufferers experience feelings of distress and feel out of control.

Dr. Wayne J. G. Hellstrom, a Professor of Urology at the School of Medicine at Tulane University and sometime consultant for Johnson and Johnson, said that men suffering from the condition often don’t manage to maintain relationships .

He has suggested that some 20 to 30% of men will experience the problem, meaning that for Johnson and Johnson and Sciele there is a very large market who would be interested in their product.

posted: Wednesday, February 17, 2010 | Categories: Erectile Dysfunction | Priligy

Scientists have called for companies launching clinical trials into premature ejaculation and erectile dysfunction to develop consensus standards in the area.

A review presented to the International Consultation on Sexual Medicine examined clinical trials into sexual dysfunction, focusing on those done over the past 20 years. They have said that future clinical trials need to have standards which would allow investigators to better conduct new trials in the field or consider evidence already gathered.

While there have been comparative studies into erectile dysfunction medications already on the market, an increased interest in premature ejaculation from pharmaceutical firms means that there are a growing number of trials into the condition.

Jannsen Cilag have already completed their trials for the premature ejaculation pill Priligy, the first pill to be approved for treatment of the condition.

However other firms are investigating potential treatments, such as topical sprays and injections.

One of the main difficulties facing scientists researching premature ejaculation is that it is even difficult to define the condition. A research paper presented at the European Society for Sexual Medicine reported that on average men with P.E lasted 1.8 minutes, compared to so-called normal men who lasted 7.3 minutes. However men with far longer lasting times have said they believe they suffer from the condition.

Jannsen accept the definition of the International Society of Sexual Medicine for the condition, namely that it involves a short time to ejaculation, lack of ejaculatory control and negative personal impact or distress related to ejaculation.

As their product Priligy is expected to be shortly available in the UK, this definition could be of use to doctors when deciding whether or not to prescribe the drug. However the vagueness of the definition demonstrates that for companies seeking to prove whether their medication helps treat the condition, there need to be very specific standards to prove efficacy.

posted: Thursday, February 11, 2010 | Categories: Erectile Dysfunction | Viagra

We have heard that Pfizer is planning a new version of Viagra that will be available over the counter. According to Campaign magazine, Pfizer is looking at a new formulation and the product will have a completely different name.

Pfizer has previously applied for a license for Viagra to be sold over the counter without seeing a doctor but this was rejected by regulators who insisted that it was essential that patients consult with a doctor prior to a prescription for this medication being written. The reason for this is that erectile dysfunction can indicate more serious underlying conditions that may be missed if the drugs that solve erectile dysfunction or impotence were more freely available.

Our hunch is that this one will not get through the regulators for the same reason as the last attempt. Viagra is available under Patient Group Direction in the UK, where the treatment is prescribed by a pharmacist after a consultation.

The Viagra patent expires in 2012, after which time the price should come down markedly as generic versions become available on a legal basis.

posted: Sunday, January 24, 2010 | Categories: Erectile Dysfunction

A recent survey revealed that forty per cent of men over the age of forty suffer from erectile dysfunction. As men get older, perhaps unsurprisingly, that number becomes significantly higher. Many men find the subject extremely difficult to discuss, either with a doctor or with a partner.

Many men also worry about their perceived inability to satisfy their partner. This fact might feel particularly significant if you are a 65-year-old man with a partner who is 25 years your junior. Apparently, however, this is not the case for one particular 65-year-old.

Michael Douglas has revealed the secret of his successful marriage to his equally famous, Oscar-winning spouse, Catherine Zeta Jones: As well as blessing the fact that Zeta Jones “likes older guys”, Douglas has admitted that the success of his ten year marriage to the Hollywood siren it not down to roses or chocolates but rather to the fact that “some wonderful enhancements have happened in the last few years - Viagra, Cialis - that can make us all feel younger.”

So it seems that no matter how famous, wealthy or successful you are there is no need to feel any embarrassment about the need to take erectile dysfunction medication if there is a clinical need: rather be grateful that it exists and have fun!

posted: Friday, January 15, 2010 | Categories: Erectile Dysfunction

Pzifer and Eli Lilly will be feeling a little nervous after experimental drug firm Vivus Incorporated this week announced that their new erectile dysfunction medication, Avanafil, has quicker reaction times than both Cialis and Viagra.

In late-stage clinical trials, the drug was shown to get to work within 15 minutes, considerably quicker than the current market leaders.  Cialis starts working between 30 minutes and a few hours after it is taken, while Viagra acts within 30 minutes after it is taken.

Volunteers in the trial were given one of three doses of the medication, which is taken orally. 2/3s of those who were given the lowest dose, 50mg, achieved an erection in 15 minutes, rising to 69% of participants on the higher 100mg dose and 72% for those on the highest 200mg dose.

Patients saw improved sexual function and better sexual satisfaction. The side effects reported from the drug included headaches, flushing and nasal congestion.

Vivus said in a statement that the ‘magnitude of success in the first 15 minutes was surprising’. Their CEO LeLand Wilson added that he hoped that the drug would be available within 2 years, assuming that it is approved by regulators.

The speedy reaction time of the drug could significantly help it make an impact on the erectile dysfunction market, which though profitable is dominated by the best-known drugs Viagra and Cialis.

Vivus have quoted a study involved 1,900 patients with erectile dysfunction, 75% of whom said that rapid effect times for medication was an important part of their expectations for treatment. Dr Charles Bowden, director of Clinical Development at the company, believes that the quick reaction time of avanafil will ‘create an attractive position in the market’.

posted: Friday, January 08, 2010 | Categories: Erectile Dysfunction

Israeli scientists have developed a new way to combat erectile dysfunction – sound waves. The therapy uses shock waves which are fired into the body, ultimately helping men who suffering from erectile problems.

The therapy is pain free and works by stimulating new blood vessels to grow in the genital area. Previously developed 20 years ago, the therapy was originally intended for use to dissolve kidney stones. The waves of pressure go through the skin and are not sufficient to damage tissue, but are the right pressure to smash the stones into a sand-like consistency that is then passed out when the patient urinates.

Several studies have now shown that the therapy encourages blood vessels to grow, by triggering Vascular Endothelial Growth Factor, which signals to the body that the new vessels need to start growing. The potential for encouraging better blood flow around the body has also led to hopes that the treatment could also be used to combat heart disease.

In the trial, 20 men with an average age of 56 were recruited to take part. All were taking medications like Viagra or Cialis and most had suffered from impotence for 3 years. The severity of their problem was then measured using a system frequently used to doctors to assess impotence, the International Index of Erectile Dysfunction, a points system with a low score indicating a significant problem.

After treatment, the men saw their scores increase by between 5 to 10 points, indicating that the therapy significantly improved their condition.

The doctor leading the study, Dr. Yoram Vardi, said that the treatment was important because it could offer a biological solution to erectile dysfunction rather than controlling the condition with medication. However the treatment is still a very long way of being offered to patients and clinical trials are ongoing.

posted: Friday, December 18, 2009 | Categories: Cialis | Erectile Dysfunction | Viagra

The UK Medicines regulator has warned that patients taking herbal remedies to treat erectile dysfunction could be taking serious risks with their health.

The Medicines and Healthcare Products Regulatory Agency, the MHRA, has said that patients should avoid taking herbal ED products and should stick to the three clinically trialed remedies for the condition, Cialis, Levitra and Viagra.

The regulatory body said that often, herbal products contain unspecified chemical ingredients and are dangerous and misleading. In a statement, they said that frequently products that promised to be 100% natural were making false claims.

The products are sold either on the internet or through traditional herbal outlets. Each month, the MHRA announce that various supposedly herbal products have been discovered to contain illegal ingredients, such as sildenafil (the active drug in Viagra) or tadalafil (the drug in Cialis), though this is not declared on the ingredients list.

Both drugs should only be sold with a doctor’s prescription and can put patients health at risk if they have contra-indications for the medication.

The MHRA warned that taking medicines containing ‘random, uncontrolled quantities’ of the analogue chemical compounds could potentially cause serious reactions in patients, including strokes, heart attacks and severe hypotension.

Since 2005, the MHRA have discovered that 2/3s of the 138 unlicensed herbal products they tested contained prescription-only medications in a range of quantities.

posted: Thursday, November 12, 2009 | Categories: Erectile Dysfunction

A Korean drugs company has begun stage III trials for its new erectile dysfunction medication, Zydena. The trials are taking place in the U.S, with the ultimate aim of receiving approval from the FDA.

Dong-A are working with U.S partners Warner Chilcott PLC  to complete the trials into the drug, which will be randomized, double-blind and placebo controlled. 1,100 men are expected to take part in the trials,which will be taking place in 80 different locations across America. They are designed to look at safety as well as how effective the drug is.

In a statement, the company announced that they were hoping to complete clinical trials for the U.S and the European Union within two years.  

In 2005 Udenalfil – the medical name for Zydena - was approved by the Korean Food and Drug Administration in 2005 and went on sale there in early 2006. It was also approved by the Russian drug regulators in 2008 and went on sale there in 2009. Since it went on sale in Korea, the drug has been a fairly big seller, with over 6 million tablets prescribed for men with erectile dysfunction.

The medication is part of the same category of medication that Viagra, Cialis and Levitra belong to, phosphodiesterase type 5 (PDE-5). If it does receive approval it will be in direct competition with the more established medications.

posted: Wednesday, October 14, 2009 | Categories: Erectile Dysfunction

A company that makes medical devices, Medtronic Inc, this week announced that they beginning a feasibility study into a new treatment for erectile dysfunction that uses a stent to deliver medication to the genitals.

The study is called Zen and the company have said they are aiming to enrol 50 subjects in up to 10 medical centres around the US over the coming year. The company are hoping that the new treatment method will provide men who do not respond well to PDE5 inhibitors, namely Viagra, Cialis and Levitra, with another option.

A stent is a small device that is inserted into a natural passage or conduit in the body. They are usually used to treat coronary heart disease by opening clogged arteries. Medtronic have designed a special stent that will be inserted into the pelvic artery to counteract coronary heart disease-related impotence.

They plan to work with urologists and interventionists at the different medical centres who take part in the trial and hope that results will be available in 2011.

posted: Monday, September 21, 2009 | Categories: Cialis | Erectile Dysfunction

Scientists from New York have said that a topical cream being developed for the treatment of erectile dysfunction could be safer than the traditional pill method currently used.

Studies have been done showing that the three main ED medications Viagra, Cialis and Levitra could pass through the skin in tiny capsules, producing fewer side effects and speeding up the action of the drugs considerably.

At the moment, some men experience side effects from the medication, which can include blurred vision, headaches or upset stomachs. Men with heart problems are also advised to be extremely cautious when using the tablets or even avoid using them entirely.

The topical cream might avoid these problems, as by applying the cream specifically to the genital area the active ingredients of the medication would be confined to a single area, rather than circulating widely around the body.

The science behind the new innovation is nanotechnology, which uses tiny particles smaller than a grain of pollen. One of the lead researchers, Dr Kelvin Davis, said that the nanoparticles containing Cialis, nitric oxide and a new medication called sialorphin, entered the body extremely quickly and so cut down the response time to a few minutes, fulfilling men’s wish for a fast-acting medication.

The team published the results from the tests, which were done on rats, in the Journal of Sexual Medicine. They warned however that the topical cream was unlikely to be ready for general use for at least a decade.

The connection between unhealthy living and erectile dysfunction has long been highlighted by the medical community and the media. However, new research from The Second University of Naples has established that women should be wary too due to a strong link between high cholesterol and female sexual dysfunction.The research found that women who had high cholesterol had not only their general health affected but also their ability to be sexually aroused. High cholesterol, also known as hyperlipidemia, causes arteries to get blocked restricting the flow of blood around the body. As with men, women need an increase in blood flow to their sexual organs in order to achieve good sexual functioning.

During the study the researchers looked at a large group of premenopausal women, some of whom had hyperlipidemia and some of whom did not. The data showed that there was a significantly higher level of sexual satisfaction, orgasms, lubrication and arousal in those women without the condition.

It was found that one third of the women suffering from high cholesterol reported lower than average scores on a sexual function questionnaire. These women would therefore be classified as suffering from female sexual dysfunction, a condition that statistically will only affect nine percent of women with normal, healthy cholesterol levels. Interestingly the levels of sexual desire were the same in both groups of women.

In a related study, a team at the University of Milan found that female sexual dysfunction was also associated with diabetes, obesity and an underactive thyroid gland.

Geoffrey Hackett, a urologist at the Holly Cottage Clinic in Fisherwick said, "These two papers suggest there are strong connections between women's sexual arousal and organic diseases in the same way that men's sexual problems arise."

This research will almost definitely change the way in which female sexual dysfunction is treated and opens the way for the use of statins to treat the condition in the future.

posted: Thursday, August 27, 2009 | Categories: Cialis | Erectile Dysfunction | Levitra | Viagra

Bayer Pharmaceuticals, the manufacturers of the erectile dysfunction medication Levitra, have submitted an application to have a new formulation of the drug registered in the European Union.

Bayer are excited about the new formula, which they hope will improve the currently flagging sales of the medicine. They plan to sell the medicine in the form on an orodispersible tablet containing 10mg of vardenafil, the medical name for Levitra. The pill will dissolves on the tongue in seconds. This would give Levitra an edge of the competition, as both Cialis and Viagra need to be taken with water.

They hope that the new type of pill will prove more discreet and convenient, as men will not need to interrupt foreplay to get a glass of water to take their medication with.

A representative from Bayer, Jean-Philippe Milon, said that the new formula marked a ‘strategic milestone’ in the development of ‘innovative and easy-to-use men’s health products’.

The pharmaceutical company have completed two large phase III clinical studies which they say showed the the new formulation is as safe and effective as the current pills on the market.

posted: Tuesday, July 28, 2009 | Categories: Erectile Dysfunction | Viagra

More and more men are seeking treatment for erectile dysfunction, new figures have revealed. Prescriptions for Viagra and other ED medications like Cialis rose by 6% this year compared to last, with a total of 1.98 million men getting prescriptions from their doctors.

The rise in men seeking prescriptions from licensed doctors is good news for the MHRA who have been campaigning against the trade in counterfeit drugs over the internet. Many men feel too embarrassed to visit their GP about their erectile function problems, though estimates suggest 1 in 10 men over 40 will experience impotence. This means that they go on the internet and often get taken in by illegal firms.

There are a few legal clinics, such as ours, that only use Royal Pharmaceutical Society registered UK pharmacies and General Medical Council registered doctors, but there are many more illegal firms operating.

The rise in prescriptions means that the NHS is paying £35 million a year for the medications. Viagra is still the most popular drug – 1.18 of all the men getting treated last year went for the famous blue pills.

Sandra Gidley, the Liberal Democrat health spokeswoman, said that despite the cost no one would begrudge the men help in treating their impotence.  However she warned that anti-impotence drugs should not be seen as a ‘cure’ as impotence could be a symptom of an underlying health conditions such as diabetes or a heart condition.

posted: Thursday, July 23, 2009 | Categories: Erectile Dysfunction | Viagra

If the slew of emails I get in my inbox are true, then even though I’m a women, I probably could have grown my own penis if I had taken up the spammer’s myriad offers to make it “bigger and stronger”.

No woman would ever need to complain to her girlfriends over a glass of wine about a disappointing night , when spammers are promising drugs that would enable the lucky stud to “give her the most powerful orgasm of her life!” (That is a direct quote – the same email also advised, “Attack Your Lady Harder” which is seems a little at odds with the promised orgasm, but still).

However Pfizer and Microsoft Corps have come together and decided to do something to save me from the spammers.

On Thursday, they announced that they had filed a total of 17 lawsuits against individuals associated with the sale and distribution of Viagra. By filing the lawsuits they now can subpoena the internet service providers to track down the defendants and hopefully do something to halt some of the deluge of spam.

The two companies said that 1 in 4 spam emails offer Viagra, which Pfizer manufacture. Often consumers are duped into thinking they are from genuine Pfizer suppliers, only to end up with counterfeit medication that is more likely to result in a heart attack than an earth-shattering night of pleasure.

Honestly, 17 lawsuits are unlikely to make much of a difference to the amount of spam flying about the internet, or indeed to the numbers of consumers buying illegal medication on the web, but it is the first time that a pharmaceutical company has teamed up with a nanotechnology firm to at least try. For Pfizer, even making a marginal difference to the amount of counterfeiting of Viagra can net them millions of dollars worth of lost revenue.

I still think I will continue to get lots of offers to  make my imaginary willy bigger and stronger, but I shall take comfort in the fact that Pfizer and Microsoft are on my side. Sort of.

posted: Friday, July 17, 2009 | Categories: Erectile Dysfunction | Sexual Health | Viagra

A new NHS pamphlet encouraging pensioners to rev up their sex lives with Viagra and dating agencies has been criticised as a waste of public funds. The 60-page booklet cost £13,700 and has been distributed to older people in the Medway area of Kent.

As well as informing women that sex boosts oestrogen and so can prevent heart disease and osteoporosis, it also advised that they could improve their bladder control as regular sessions in the bedroom would strengthen pelvic floor muscles.

The booklet advises the older generation about the benefits of the erectile dysfunction medication Viagra, which is often used by more elderly men to restore their ability to achieve an erection, which decreases with age. It is believed that 50% of men over 40 will experience the problem at some point. It also warns that everyone who is sexually active – regardless of their age – needs to get regular sexual health check-ups.

The Tax Payers Alliance, which monitors use of tax-payers money, have lambasted the booklet as an “obscene” waste of money, suggesting that it could be viewed as an interference with people’s private lives and that the money could have been spent on operations.

However Tricia Butt, development manager at Medway Older Persons Partnership, who supported its publication, has rejected the criticisms. She pointed out that old age didn’t mean the end of “libidinal energy” and said that if it helped people, then it could not be called a waste of money.

posted: Thursday, July 02, 2009 | Categories: Erectile Dysfunction | Viagra

Further proof of the potential for other uses of the erectile dysfunction drug Viagra came this week when it emerged that the medication saved the life of a baby who was given just weeks to live.

Alfie Oliver was diagnosed with narrow blood vessels around his lungs after he was born and at just a few days old underwent a series of dangerous heart operations to repair the condition. After he suffered a heart attack, his doctors believed there was nothing more to be done to save his life.

The baby was diagnosed with two different conditions, transposition of the great arteries – meaning that his pulmonary artery and aorta were in reversed positions – and pulmonary hypertension. At sixteen days, he was operated on to reverse the position of the arteries but despite a promising start was readmitted to hospital.

Hope came when Great Ormond Street doctors heard about his prognosis and suggested that doses of Viagra might open up his narrow vessels and improve his circulation. The treatment worked, and now Alfie has reached his 1st birthday, a milestone his parents and family thought they would not ge to see.

The medication has been particularly successful as due to his age, Alfie has experienced none of the side effects usually associated with the drug.

Previous studies have already shown that Viagra can relieve pulmonary hypertension in newborns and may be particularly useful in developing countries, which cannot afford the more expensive drugs usually used to treat the condition.

posted: Tuesday, June 16, 2009 | Categories: Erectile Dysfunction

Men suffering from impotence usually will visit their doctor to get a prescription for one of the three erectile dysfunction medications to help them perform. However a new invention claims that bursts of light may be a non-medical solution to the problem.

The’ Lovelight’ has been shown to improve men’s sexual performance by emitting bursts of fluorescent light. Early tests seem to indicate that the device helped 3 out of 5 have a better experience in bed. The group of volunteers, who were suffering from a variety of sexual problems ranging from lack of desire to impotence to the inability to achieve orgasm, for half an hour were exposed to the light in the morning for two weeks.

Following the trial period, 3 out of the 5 men reported that their problem had gone away, compared to the second test group who were exposed to dim rather than florescent light. The team of researchers, from Siena University in Italy, believe that the improvement was due to the light promoting reaction in the brain’s pineal gland, which plays a role in sexual function.

posted: Friday, March 13, 2009 | Categories: Erectile Dysfunction

Scientists in Italy have made a rather remarkable discovery: hydrogen sulphide - the vile smelling gas emitted from rotten eggs - has a role to play in the formation of penile erections. The discovery was made in a rather bizarre way: hydrogen sulphide was injected into the penile tissue of the discarded sex organs of eight male to female transsexuals.  The discovery was made by Professor Giuseppe Cirino of the University of Naples.

The role of hydrogen sulphide gives researchers a new target for potential erectile dysfunction drugs.  The market leaders - Cialis and Viagra - only have around a 75% success rate and although some current ED drugs will work for some patients but not others, we estimate that around 20% of men who suffer from erectile dysfunction do not respond to any of the pharmaceutical treatments currently available.

The effects of sildenafil (the active ingredient in Viagra) on men suffering from erectile dysfunction was, like so many drugs, discovered by accident.  It was only after observations were made in wide-scale clinical trials of sildenafil in men being treated for angina that the role of nitric oxide in the formation and maintenece of penile erections was actually identified.

The new research will undoubtedly lead to the development of drugs for clinical trial in this very lucrative field so there will be more news on this front in the next few years - that much can be guaranteed!

posted: Wednesday, March 11, 2009 | Categories: Erectile Dysfunction

The glamorous actor/tv presenter/model Kelly Brook has recently been embarrassed after it was revealed that a Chinese firm of condom manufacturers have been using her image to promote their brand of condoms, without her permission. The sexy photo, featuring Brook in a shiny gold bikini, has been printed onto the boxes of 12 and sold in a variety of Chinese supermarkets. Chinese Eyesome (their name is wildly appropriate considering the photos), the manufacturers, have also used photos of the American Beauty actress Mena Suvari.

The illicit use of the celebrity photos follows on from the scandal caused when another Chinese firm selling erectile dysfunction medication ran television adverts using those figureheads of virility, David Beckham, Sean Connery and Keanu Reeves. The Beckham ads show dodgy footage of the football star running across a pitch, before the even dodgier voice-over informs us that the tablets are “the secret weapon with which I can satisfy Victoria” and help him “keep strong and running on the football field.” An even better recommendation comes from the Matrix actor (ish), who lets us know, “After using USA Selikon to wash out my kidneys I had a very happy surprise. Of course, the happy surprise also belongs to my girlfriends!”

We have a few questions. Firstly, what exactly does it mean to wash out your kidneys? It sounds not only unappealing but very unerotic. Then, how would showing a Western celeb on a Chinese packet of condoms put a couple in the mood for sex? Getting naked is hard enough without being confronted at the salient moment by a stunning, unobtainable girl who looks nothing like you/your partner. Clearly marketing in the Chinese sexual health industry is all about celebrity ‘endorsement’ and absolutely nothing to do with legality or morals. Still, we just want to see whose photo gets used next...

posted: Monday, March 02, 2009 | Categories: Erectile Dysfunction

We’re not sure if Pfizer, the makers of Viagra, will be overly loving this celebrity endorsement but superstar rapper Kanye West has dedicated his new single to extolling the popular wonder drug. The single is taken from 88-Keys debut album The Death of Adam and has been co-produced by Kanye.

Entitled “Stay Up (Viagra)”, the track sees the massively popular musician envisaging an old age when perhaps his potency is waning slightly. The lyrics - erm – poignantly capture the trauma faced by millions of men suffering from E.D. “What she got is so Niagara", he raps sensitively, “Make a young n***** straight need Viagra.” The song continues eloquently, “Just to keep from all the ‘tee-hees’ and laughter/Her telling her home-girls that he couldn’t stay up”.

Arguments from the partners of ED-afflicted men pointing out that they only ever have reacted sensitively to the condition and would never think of tee-heeing have not yet been responded to. Mr. West has been filming a searing video to accompany his oeuvre. It depicts him and his friend and producer 88-Keys as senior citizens, roaming the streets of Hollywood with what MTV describes as some “honeys” on their arm.

We do hope Lilly and Bayer, makers of Viagra-rivals Cialis and Levitra, don’t get too jealous. What’s next – Fifty-Cent and Snoop-Dog promoting their medications? If any representatives from the companies are reading, please, please, please consider it – you would be making our year…

posted: Tuesday, February 17, 2009 | Categories: Erectile Dysfunction

A group of GPs has called for a rethink of the NHS’s current guidelines regarding the treatment of erectile dysfunction, saying that the current policies are ‘discriminatory.’ Pulse, a weekly medical publication, has reported that as GPs get ready for a flood of patients seeking the new one-a-day treatment recently approved by the European medicine regulatory body, questions are starting to be raised as to the availability of free treatment.

At the moment, only 15% of patients are entitled to free treatment and the current Department of Health recommendation is that those patients should have enough pills for a sexual encounter once a week though as many as one in ten men suffer from the condition. Patients must have one of 12 conditions to be entitled to free treatment. The new treatment is a lower-dose version of the popular pill Cialis, which taken once a day would allow for spontaneous sexual encounters whenever desired.

Professor Mike Kirby, a former urology specialist and visiting professor at the University of Hertfordshire said that he did “not think it is right to keep free treatment restricted full stop, and it’s a great shame that it has not been reviewed.” Another doctor, Patrick Wright, said that he found it odd that someone with mild diabetes was eligible while someone with cardiovascular disease was not.

The Department of Health said that while they believed that one treatment per week was suitable for most patients, it was recommended that doctors treat on a case-by-case basis, meaning that some patients might be prescribed more than one treatment a week.

posted: Tuesday, February 03, 2009 | Categories: Erectile Dysfunction

Younger men suffering from erectile dysfunction have a doubled risk of developing heart disease, according to scientists from the renowned Mayo Clinic in America. Studying 1,402 men over ten years, they found that the highest risk for developing coronary artery disease was in younger men aged between 40 and 49. Even more alarmingly, the research indicated that men with erectile problems were 80% more likely to develop heart disease.

The Mayo Clinic has previously done two other studies examining the link between heart problems and erectile dysfunction. One predicted that younger men with erectile issues were more likely to develop both conditions, but until now they were not able to study the men over a long period of time.

The study was not conclusive as to why the two conditions are linked. Some doctors have theorised that erectile dysfunction and heart disease are caused by a common disease process. It is possible that the same build up of fat in the heart that blocks the heart’s arteries may block the arteries in the penis first, therefore causing the dysfunction. It has also been suggested that over time, arteries can lose their elasticity which may also contribute to disease, and this would first be noticed in the penis.

Erectile dysfunction is a common disorder and becomes more common as men age. Of men aged over 40 it affects between 5 %and 10% of men, and by the time they reach 70 this has increased to between 40% and 60%. The research indicates that with those who are diagnosed early – in their forties – doctors should consider this an early sign marking the patient as a likely candidate for heart trouble and should therefore take appropriate steps to treat this.

posted: Monday, January 26, 2009 | Categories: Erectile Dysfunction

We are all familiar with the idea of ‘brewer’s droop’, where men who drink too much are unable to achieve or sustain an erection. While undoubtedly consuming excessive drink may impair a man’s ability to perform in bed, a new study has suggested that conversely, a small amount of alcohol can in fact improve erectile function.

Australian scientists have published research in the Journal of Sexual Health that indicates that men who drank a moderate amount of alcohol reported 30% less sexual problems than tee-totallers. The researchers from the Keogh Institute for Medical Research, in Western Australia, carried out a study of 1,580 men. They found that amongst low-risk drinkers (that is those who consumed up to 4 drinks a day for up to five days a week) there was a favourable link with positive erectile function.  Men who drank at weekends or binged had a lower rate of erectile dysfunction than those who only drank once a week or not at all.

However, they did find that the men who performed worst were the heavy drinkers who had given up, those who smoked and those with heart disease. As binging is associated with poor health, it might be argued that short-term bingers might not see their sexual performance affected, but long term as their health deteriorate they might begin to suffer.

The study suggested that better performance might be linked to the freeing properties of alcohol, pointing out “alcohol may increase sexual desire through disinhibition”.

posted: Wednesday, January 14, 2009 | Categories: Erectile Dysfunction

A new study has revealed that obese men may be at risk of suffering from erectile dysfunction. Published in the Journal of Sexual Medicine, the findings showed that obese men often have a significantly lower level of hormones, which affects sex drive. Studying a group of nearly 2,500 men seeking treatment for erectile dysfunction, the researchers discovered that excess weight was a significant factor in physical causes of sexual dysfunction, though it did not play a part in psychological or relationship-based causes.

They found a direct link between the weight of the patient and their levels of testosterone, which decreased as the weight increased. Testosterone is the key hormone in determining sex drive. Two out of three obese patients had low testosterone and it was also shown that overweight patients had low blood flow to the penis. A previous study has already linked excess abdominal fat with erectile problems.

The study will perhaps provide men with that extra push to keep their health in check. Diabetes, heart disease - such threats can perhaps seem vague and far off in the future. Reduced potency may be enough of a threat to prompt serious action. It is particularly unfortunate that obesity can reduce a man’s ability to have sex for sex is actually very good exercise; a vigorous session can burn as many calories as time on an exercise bike…

posted: Tuesday, December 09, 2008 | Categories: Erectile Dysfunction

For a considerable time, scientists have suspected that there may be a link between sleep apnoea and erectile dysfunction. Now a study published in the September edition of the American Journal of Respiratory and Critical Care Medicine has gone a long way towards proving it.

Sleep apnoea is a condition where there are pauses or shallow breathing as someone sleeps. The pauses can last from a few seconds to minutes, and typically occur between 5 and 30 times an hour. The condition can seriously disrupt the sleep patterns of those who suffer from it and therefore impact on their daily lives, but the new information indicates that it can also be a major problem for their sex lives.

Research done at the University of Louisianna has shown that when mice suffered from chronic intermittent hypoxia - the same lack of oxygen those who have sleep apnoea experience - it resulted in a decrease in their daily spontaneous erections of 55%. After five weeks, there was a sixty-fold decrease in the number of times the mice attempted to mate. The mice responded well to two treatments, firstly when their oxygen levels were returned to normal and secondly when they were given Cialis, the erectile dysfunction medication, which increases the availability of nitric oxide.

The study has implications for the diagnosis and treatment of some forms of erectile dysfunction. Writing on the website of Urology Today, researchers from Seoul, who have also just completed a study into the links between the two conditions, recommended that “male patients with OSAS (obstructive sleep apnoea syndrome) should be screened for erectile dysfunction”. This would seem to work both ways, in that by testing patients with erectile dysfunction for sleep apnoea, doctors could gain a better understanding of the cause of their condition. As we discover more about the relationship between sleep patterns and erectile function, the hope is that better treatments for condition will follow.

A study has recently published findings stating that male circumcision does not impair male sexual function, but in fact may improve the sex lives of those who have had the procedure done. The study, lead by John Krieger of the Universit y of Washington, followed 2,684 Kenyan men over three years , of whom 98% stated that they were happy with their circumcision. In the Journal of Sexual Health, which published the study, Kreiger revealed that rather than impairing sexual performance as some believed, most of the men experienced “both greater penile sensitivity and easier use of condoms.”

The study will perhaps have the greatest impact in Eastern and Southern Africa, where the battle rages to control the HIV epidemic. In keeping with the recommendations of the World Health Organisation, circumcision is seen as a crucial weapon in HIV prevention programs amongst high-risk heterosexual populations. Krieger’s findings will certainly help to promote the procedure.

In the West, however, the study is an interesting addition to the debate over whether or not circumcision is beneficial. Once popular in both America and the UK, the rates of circumcision have dropped considerably, though in certain religious communities the procedure is still common. Regardless of whether it is medically beneficial or not, doubtless many men who agree to undergo the procedure will be reassured that it is unlikely to have had any negative impact on their sex lives.

posted: Monday, October 06, 2008 | Categories: Erectile Dysfunction

Online shopping in a very modern phenomenon: there is no need to trawl around shops on the off chance of finding something you will like or, if you have a particular product in mind, finding that it is not stocked or out of stock.

In the last five years Internet shopping has taken off, after an initial scepticism from customers who were not happy about making payments online. As our free time has more demands made upon it, it is hardly surprising that we want to shop in a more convenient and time effective way. Shopping online avoids the crowds of the high street and new systems have been put in place to make giving your card details far more secure than only a few years ago.

So this is all great news if you want to buy a CD, a new pair of shoes or a television set. Should we as consumers, however, be buying Erectile Dysfunction medication from online sources rather than the more traditional method of having a face to face consultation with a GP?

A survey just completed in the United States says that, for American men at least, the answer is a resounding yes. Indeed the survey that is published in the August edition of Mayo Clinic Proceedings found that the consultation to buy Erectile Dysfunction medication on line was actually more thorough than the face to face consultation with a physician.

In the United States online prescribing is also known as e-medicine prescribing. By interviewing 1000 men, 500 of whom had a face to face consultation with their own physician and half of whom had an online consultation, it was found that e-prescribing "outperformed the traditional system in most of the safety variables tested." The authors of the survey noted that 100 percent of the e-medicine clients received follow up information while only 51.8 percent of those who saw a physician were supplied with all the relevant information.

An Erectile Dysfunction consultation at The Online Clinic takes a matter of minutes. It is, however, comprehensive, extremely thorough and specifically gauged towards the patient’s history and suitability for this specific condition. No medication is prescribed without the doctor being certain that it is the best form of treatment for a patient. The patient is also provided with further information on erectile dysfunction with his first order. We also recommend that every new patient allows us to write to his GP so that they can be kept abreast of all medications prescribed to that particular patient.

posted: Sunday, August 24, 2008 | Categories: Erectile Dysfunction

Viagra, Cialis and Levitra are extremely effective treatments for mild to moderate cases of erectile Dysfunction. For most men suffering with ED, these PDE-5 inhibitors provide the most suitable option. Viagra has been available for over ten years and has helped millions of men across the globe. There are, however, men for whom oral Erectile Dysfunction medication is not an option. For these sufferers it might then seem that there is no real option available to them. This, however, is not the case.

Dr Peter Muench, a prominent urologist has said this week that the improvements in penile implants over the last few years mean that it is the best and most suitable option for many men suffering from serious ED.

The kind of Erectile Dysfunction cases which are untreatable by oral medication are usually those which have been caused by prostate cancer. Research has shown men who are prescribed Viagra post operatively have a far greater chance of achieving a spontaneous erection after three months. Some men, however, do not respond to this method of treatment and it is this category of men that Dr. Muench thinks is most suitable for penile implants.

He says that implants have the best level of satisfaction in both the patients and their partners than any other type of treatment, including oral medication. He says that the implants provide maximum rigidity, durability and concealability. Improvements in the implants have also meant that the risk of infection is now much less than it used to be thanks to the fact that the manufacturers coat the implants in antibiotics.

Dr. Muench also says that a penile implant not only restores erectile function but improves on it. He says that a penile prosthesis can actually help a man to perform better than his peers and better than he did in his prime because the implant stays erect until he chooses to deflate it.

Dr. Muench, perhaps, slightly overstates his case in suggesting that a penile implant will help a man to become some kind of super stud. Most of the men who have this operation would probably be delighted in the fact that they have restored erectile function without having to perform all night to prove it!

posted: Thursday, August 14, 2008 | Categories: Erectile Dysfunction

New research from the University of Chicago debunks a popular myth about Erectile Dysfunction. In it scientists suggest that ED is not an inevitable part of the aging process but rather that it is related to a number of factors. The fact that physical health, that is to say general well being, is one of the factors is not surprising, neither perhaps is a man’s mental health and well being. What the research has also found, however, is that social demographics and past sexual health history also play a significant role in whether or not a man will suffer from ED.

The researchers interviewed 1455 men aged between 57 and 85. They found that overall physical health was the main factor that indicated whether or not a man would suffer from erectile problems in later life. Interestingly, the scientists also discovered that having had an STD also seemed to have a significant effect on people’s sexual health in later life. A man who had suffered with an STD at some point in his life was five times more likely to find that sex was not pleasurable, even though the complaint had been discovered and treated.

Also the scientists found that mental health had a large bearing on Erectile Dysfunction issues. It was found that men who had mental health issues or were experiencing problems in their relationships were significantly less interested in sex than men in happy relationships with no mental health issues. These men, with decreased sexual interest, also found it much more difficult to achieve orgasm.

The report also suggests that demographics and cultural factors play a role in a man’s sexual performance. The survey found that black men were twice as likely to have a lack of interest in sex in the 57 to 85 year old age group and were more likely to report that they climaxed too early.

These statistics are, of course, based on the answers to questions and are, therefore, rather subjective. What does climaxing “too early” actually mean? How long should it take for a man to achieve orgasm? There is probably some truth in the statistics but unless the subjects were actually studied under laboratory conditions, their sexual performance is determined by how they themselves regard it and the expectations that they themselves have. At the end of the day, however, every man has different expectations and different perceptions of how they perform.

posted: Thursday, August 07, 2008 | Categories: Erectile Dysfunction

Men are notoriously bad when it comes to matters concerning their health. Not all men of course but, if you pay heed to the statistics, the vast majority. Men are far less frequent visitors to their GPs and, it seems, are far less aware of their own bodies and the heath problems that they may incur simply due to the fact that they are men.

There are magazines which purport to be about ‘men’s health’ though if one has a quick look past the image of a ripped fitness model on the cover it quickly becomes apparent that these magazines are about building ‘better’ bodies and by that we do not necessarily mean healthier. These magazines are intended for those who want to look better, ‘get your beach body in ten days’, ‘how to get killer abs’ or ‘how to win a woman’ seems to be the main emphasis.

There are health pages in the daily papers but the stories are usually more sensationalist than everyday health matters. Women on the whole seem far more knowledgeable when it comes to their bodies; many go for cervical smears and check their breasts for lumps. I doubt the percentage is comparable to the number of men who regularly check their testicles for lumps. So is it machismo or ignorance that makes many men so lackadaisical about their health? Perhaps it is a combination of the two.

The problem is serious enough, however, for the UK Government to be launching a new initiative aimed at men over forty. A survey which has just been published has revealed that only ten per cent of men in their early to mid forties realise that they may suffer from erectile dysfunction in the next ten years of their lives even though the problem affects forty per cent of all men over the age of forty. Most of the men who were questioned did not realise that erectile dysfunction could be symptomatic of serious conditions such as diabetes or heart disease. The new campaign will be called 40over40, a reference to the percentage of men who will suffer from ED over that age.

Erectile dysfunction is, thanks to drugs such as Viagra, Cialis and Levitra, a treatable condition in a way that it never was only a decade ago. Regardless of that fact, however, it is time for men to pay more attention to their health and well being. After all, to cite the old saying, it is the most valuable thing that we will ever own.

posted: Tuesday, December 04, 2007 | Categories: Erectile Dysfunction

We have just seen some information on a product called Prelox which claims to solve erectile dysfunction in a completely natural way.  The compound consists of Pycnogenol, an antioxidant derived from a certain time of maritime pine tree, and L-Arginine aspartate, an amino acid.  The compound has been awarded a patent in the US for the treatment of erectile dysfunction and the research that we have read seems to suggest that this product has a high rate of success.  The full study is to be published in the International Journal of Impotence Research.

Prelox is a food supplement so it would be required to be taken on a regular basis rather than just as a one off when sex was desired as is the case with the conventional treatments for erectile dysfunction.  According to the published information that we have seen, Prelox has a satisfaction rate of around 85% which is pretty amazing.  What is not clear from the research is how bad the erectile function in each of the patients was to begin with.  Further information can be found at Prelox

posted: Thursday, November 22, 2007 | Categories: Erectile Dysfunction

NexMed has filed for approval in the US of its transdermal patch which delivers alprostadil to solve erectile dysfunction.  Alprostadil already exists in the UK as a urethra suppository (MUSE) and an injection (Caverject.)  If no further information is requested then approval could come in 8 months.

No data was available for the success rate of this delivery mechanism but it may be suitable for cases that cannot be treated with first line solutions such as Viagra.  The inconvenient delivery mechanism for current alprostadil prescriptions has meant that the treatment is not popular with most men.

We will bring more news as and when we have it.

posted: Friday, August 31, 2007 | Categories: Erectile Dysfunction

We have been bringing you news about the development of a potential new treatment for erectile dysfunction called Bremelanotide.  Unfortunately, this first in class melanocortin agonist drug will not be progressing to Phase 3 trials at the current time.  This follows representations from the US Food and Drug Agency, which did not believe that the efficacy and the associated risks/benefits justified the trials going ahead. Apparently the success rates from the phase 2 trials were not too impressive and there was a high incidence of raised blood pressure.  It is thought that the FDA was amenable to a progression to phase 3 trials on the basis that the drug would be a second line treatment where the existing PDE5 inhibitors, such as Viagra, had not worked.  This appears to be unacceptable to the patent holders at the current time.  If and when we get further news, we will post further information here.  For additional information, please have a look at the Palatin Technologies website.

posted: Thursday, August 16, 2007 | Categories: Erectile Dysfunction

An article has appeared in Perspecives on Prostate Disease which flies in the face of traditional advice dispensed to men recovering from a radical prostatectomy (complete removal of the prostate gland.)  The lack of erections following prostate surgery has been attributed to nerve damage which should heal over time. It has been advised that men should wait until the nerve damage has healed before they attempt to get an erection but it would appear that allowing the penis to remain flaccid for an extended period of time (sometimes up to 2 years before complete healing has taken place) could actually damage the prospects of ever being able to get a normal (i.e. unaided by drugs or other medical intervention) erection ever again.

By remaining flaccid for long periods of time, the penis becomes deprived of oxygen and will become similar to scar tissue where the lack of flexibility may prevent vessels within the penis from expanding as they become filled with blood.  If the penis is exercised then it is more likely that normal unaided function will resume with the passage of time.

Research into penile rehabilitation following prostate surgery is not perfect and we recommend that patients discuss this matter with their consultant before they embark on a course of action which could be damaging. If you are approaching The Online Clinic to discuss erectile dysfunction following a radical prostatectomy then it is important that you disclose this information.

posted: Thursday, August 02, 2007 | Categories: Erectile Dysfunction | Mens Health | Smoking

A study in China involving 7,684 men has concluded that smoking can be a major contributory factor to erectile dysfunction.  This is something that we have long suspected but this authoritative piece of research to be published in the American Journal of Epidemiology demonstrated that the statistical link is significant.

There appeared to be a direct correlation between the quantity of cigarettes smoked and the incidence or severity of the erectile problems.  There also appeared to be a stronger association in participants who also had diabetes.  The study included men aged 35-75 who did not have any vascular disease.

Help is at hand here if you want to give up smoking.  We are prepared to prescribe Champix for smoking cessation and there are a number of treatments for erectile dysfunction, including Viagra , that we are also prepared to prescribe.  As always, whether we will prescribe something will depend on your medical circumstances so you must complete a consultation form before we can make a decision.

posted: Friday, July 13, 2007 | Categories: Erectile Dysfunction | Mens Health | Womens Health

Back in January we brought you news of an exciting new drug in development which can be used to treat erectile dysfunction in men and hypoactive sexual desire disorder in women.  We now have information that the Phase IIb trials for use in men were a success and a meeting has been arranged with the FDA in August to discuss the results and to run through the requirements for the Phase III trials.  Bremelanotide tackles erectile dysfunction in a completely different way from the current generation of drugs such as Viagra.  Bremelanotide targets the central nervous system and is the first medication in a class known as melanocortin agonists.  Because of the way that this new medicine works, it is unlikely to be contraindicated for patients with heart problems or who use nitrates.  Although it will be a while before this medication is available to prescribe, initial findings do appear positive.




Viagra | Cialis | Levitra | Xenical | Acomplia | Reductil | Propecia | Intrinsa | Champix | Tamiflu

Professional medical advice will be given before buying any impotence or erectile dysfunction treatments such as Viagra, Cialis and Levitra. We also offer advice on hair loss treatments and solutions such as Propecia. Please get in touch with us for weight loss treatment including Acomplia, Reductil and Xenical weight loss pills. Influenza can also be treated with Tamiflu or Relenza. If you are trying to stop smoking we can prescribe Champix. Women with hypoactive sexual desire disorder can be treated with  Intrinsa. Consultations take place online and medication is despatched to addresses in the UK for next day delivery.