HomePain ManagementCo-dydramol


Co-dydramol is used to relieve mild to moderate pain and is for short-term use.

What is Co-dydramol?

Co-dydramol is an analgesic, containing two active painkillers - dihydrocodeine tartrate and paracetamol. The opioid dihydrocodeine works by preventing pain messages being sent to the brain via the nerves; the intensity of pain is therefore reduced. When you have an injury or pain, prostaglandins are released; paracetamol stops this chemical release and therefore the pain. Paracetamol also lowers your temperature by interfering with the temperature-control region of the brain.

Can I get Co-dydramol online?

Co-dydramol can be prescribed online if you complete a brief consultation form. The questionnaire will require you to provide a brief medical history to allow us to make a prescribing decision. You will normally have a response within 30 minutes.

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How to use Co-dydramol

One or two Co-dydramol tablets can be taken every 4 hours, if required, with up to 8 tablets in any one day (24 hours). Swallowed whole with water, the tablets are taken with or after a meal. These tablets are not for long-term use but should be used only for as long as your doctor tells you. Your doctor will let you know when to take and when stop this medicine. The dose may be lowered in people 65 years of age or older. Alcohol should not be consumed while taking this medicine. Get medical help immediately if you take too much Co-dydramol and, if you forget to take your tablets, take them as soon as possible but do not take another dose for 4 hours or more. Note that symptoms such as feeling/being sick, sweating, and changes in heart and breathing rate can occur if you take too many or stop the tablets.

Who can use Co-dydramol?

Co-dydramol is for adults and children 12 or more years old. Co-dydramol should not be used by people with an allergy to any of the tablet constituents or to opioids, have severe or bloody diarrhoea, or have lung or breathing problems including a current asthma attack. Neither should you take Co-dydramol if you are pregnant and/or breastfeeding. Notify your doctor if you have Addison's disease, a large prostate gland, underactive thyroid, gall bladder disorders, inflammatory bowel disease, low blood pressure, weak muscles, epilepsy, or any head injury; have recently undergone surgery; or have problems with the liver, kidneys, urinating, mental illness, alcohol or drug abuse.

All your recent past, current, and future medicines including those not obtained by prescription should be disclosed when discussing taking Co-dydramol with your doctor. Of particular interest are opioid inhibitors (e.g., naltrexone); nervous system medicines (e.g., monoamine oxidase inhibitors, barbiturates, sleeping pills and diazepam), anticholinergic agents (e.g., atropine), anaesthetics, and muscle relaxants. Similarly, medicines treating Parkinson's disease (e.g., selegiline) and epilepsy (e.g., phenytoin), anti-sickness medicines (e.g., domperidone or metoclopramide), anti-diarrhoeals (e.g., loperamide), treatments for stomach ulcers (e.g., cimetidine), and medicines that affect the liver (e.g. rifampicin) and cholesterol levels (e.g., cholestyramine), anticoagulants (e.g., warfarin), blood pressure lowering agents (e.g., guanethidine and furosemide), oral contraceptives, antivirals, and medicines for irregular heartbeats (e.g., mexiletine), depression (e.g., amitriptyline), and mental illness may also cause concern.

Co-dydramol Side Effects

Side effects may occur with any medicine and you should always report them regardless of whether they are listed here.

Allergies can occur to Co-dydramol with signs including skin itching, rash, mouth ulcers, breathing problems, facial flushing, sweating, and drug fever. Your gastrointestinal tract can be affected (e.g., lack of appetite, nausea/vomiting, pains in the stomach, and constipation) and you may experience low blood pressure, slow/fast heart rate, urinary problems, changes in blood cell counts (meaning that you may have increases in numbers of nose bleeds, bruises, and infections), blurred/double vision and small pupils, or disorders of the nervous system such as sleep disturbances, dizziness, headaches, confusion, changes in mood, and depression. It is important to realise that taking Co-dydramol continually for a prolonged period of time for headaches, can increase headache severity/frequency. Additionally, you can become tolerant to Co-dydramol so you need more to have an effect, or become dependent on Co-dydramol so you have side effects when you stop taking it such as tremor, increased blood pressure and heart rate, sweating, more rapid breathing, and sickness.

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Pain management
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